WP3 - Mise en œuvre de l’étude d’intervention et enquête d’évaluation

This Work Package is led by Prof. Halidou Tinto from Centre National de la Recherche Scientifique et Technologique (CNRST) and founder of Clinical Research Unit of Nanaro (CRUN) as part of the Institut de Recherche en Science de la Santé (IRSS), in Burkina Faso.

For the management of the WP3, Professor Tinto can count on the close support of Prof. Kassoum Kayentao (USTTB, Mali) and Dr Valérie Briand (IRD/Epicentre, France).

WP3 is the core component of the project.

Indeed, this WP is designed to implement a multicentre, cluster randomized trial of the delivery of IPTp-SP in two parallel arms (ANC and ANC+SMC) in Mali and in Burkina Faso, to ensure its smooth execution whilst complying with the principles of GCP.

Clusters are represented by health facilities and their catchment areas. In each country, 20 clusters in the intervention arm and 20 clusters in the control arm have been selected, for a total of 40 clusters per country.

The intervention consists of the monthly administration of IPTp-SP to pregnant women through the SMC channel delivery during the four monthly rounds of SMC (from July to October) in the malaria transmission season, annually for two years.